STEAP4

Across TCGA patient cohorts, STEAP4 protein abundance is significantly associated with the RNA expression of many other genes, with 21,767 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible STEAP4-associated genes across cancer lineages are CTSG, CEACAM4, and DUSP1. Each is linked with STEAP4 in more than 5 cancer types. Because this analysis shows association rather than direction, both STEAP4-to-partner and partner-to-STEAP4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STEAP4 versus CTSG in CCRCC, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STEAP4→partner) and Y-score (partner→STEAP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	CTSG →	+1.382	+0.732	<.001	<.001	3	6
LSCC	CEACAM4 →	+0.787	+0.645	<.001	<.001	3	5
GBM	DUSP1 →	+1.597	+0.834	<.001	.003	3	5
GBM	KLF2 →	+1.291	+0.787	<.001	.007	3	5
OV	JAML →	+1.107	+0.924	<.001	<.001	3	5
HNSC	S100A12 →	+2.473	+0.797	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,767 associations by consensus.

STEAP4 vs CTSG — CCRCC

Explore this scatter interactively →