STEAP3-AS1

Across TCGA pan-cancer cohorts, STEAP3-AS1 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated STEAP3-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher STEAP3-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated STEAP3-AS1 expression acts as an unfavorable survival marker, although some lineages such as READ and ESCA show a favorable association.

KIRC, DLBC, and LGG are the cancer types where STEAP3-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.515	0.727	<.001	122	view →
DLBC	DFS	Quartile	II,III,IV	0.316	1.000	<.001	73	view →
LGG	DFS	Median	All	0.327	0.473	<.001	48	view →
KIRP	OS	Quartile	All	0.817	0.950	.004	46	view →
THCA	OS	Tertile	II,III,IV	0.874	0.989	.001	45	view →
READ	OS	Tertile	II,III,IV	0.927	0.421	.002	38	view →
MESO	DFS	Median	All	0.278	0.439	.007	34	view →
ESCA	DFS	Median	III,IV	0.591	0.320	.003	31	view →
LAML	DFS	Quartile	All	0.612	0.271	.001	30	view →
OV	OS	Quartile	III,IV	0.770	0.891	.015	24	view →
LUAD	DFS	Quartile	III,IV	0.484	0.773	.012	19	view →
UCEC	OS	Tertile	All	0.550	0.760	.008	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

STEAP3-AS1–KIRC (DFS)

Open the KIRC breakdown →