STEAP3-AS1

Across TCGA pan-cancer cohorts, STEAP3-AS1 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of STEAP3-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where STEAP3-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types STEAP3-AS1 is over-expressed in tumor, although a few such as LIHC and KICH show the opposite, repressed pattern.

HNSC, KIRC, and LIHC are the cancer types where STEAP3-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in STEAP3-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Female	II,III,IV	+0.674	<.001	11	view →
KIRC	Male	All	+0.217	<.001	11	view →
LIHC	All	All	−0.110	<.001	6	view →
LUSC	Male	All	+0.683	<.001	5	view →
LUAD	All	All	+0.302	<.001	4	view →
KICH	Female	All	−0.085	.006	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

STEAP3-AS1–HNSC

Open the HNSC breakdown →