STBD1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, STBD1 mutation is significantly associated with the RNA expression of many other genes, with 460 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STBD1-associated genes across cancer lineages are RNU6-997P, SNRPCP15, and RN7SKP95. Each is linked with STBD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both STBD1-to-partner and partner-to-STBD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-997P grouped by STBD1-low versus STBD1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STBD1→partner) and Y-score (partner→STBD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADRNU6-997P →+0.502+7.741<.001.00932
UCECSNRPCP15 →+0.062+4.010<.001.00732
LIHCRN7SKP95 →+0.204+5.268<.001.00631
LIHCRNU6-1187P →+0.356+5.647<.001.00431
LIHCRNU6-505P →+0.368+5.108.005.00831
SKCMRNU6-1216P →+0.403+3.533<.001.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 460 associations by consensus.

RNU6-997P by STBD1 expression — COAD

Box plot of RNU6-997P in STBD1-low vs STBD1-high samples in COAD.

Explore this box plot interactively →

Exploration