STAU2

Across TCGA cell cohorts, STAU2 mutation is significantly associated with the RNA expression of many other genes, with 371 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible STAU2-associated genes across cancer lineages are OR4X2, KLK12, and IFNA14. Each is linked with STAU2 in more than 1 cancer types. Because this analysis shows association rather than direction, both STAU2-to-partner and partner-to-STAU2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4X2 grouped by STAU2-low versus STAU2-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STAU2→partner) and Y-score (partner→STAU2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	OR4X2 →	+0.032	+5.369	<.001	.004	3	1
SOFT_TISSUE	KLK12 →	+1.031	+4.930	<.001	.008	3	1
SOFT_TISSUE	IFNA14 →	+0.028	+5.369	<.001	.004	3	1
OVARY	KRTAP11-1 →	+0.083	+4.222	<.001	.006	3	1
OVARY	OR2J2 →	+0.015	+3.990	<.001	.003	3	1
OVARY	SUPT20HL1 →	+0.074	+4.222	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 371 associations by consensus.

OR4X2 by STAU2 expression — SOFT_TISSUE

Explore this box plot interactively →