STAU1

Across TCGA patient cohorts, STAU1 mutation is significantly associated with the RNA expression of many other genes, with 2,091 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STAU1-associated genes across cancer lineages are MRPS15P1, MIR3619, and MIR1273H. Each is linked with STAU1 in more than 1 cancer types. Because this analysis shows association rather than direction, both STAU1-to-partner and partner-to-STAU1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MRPS15P1 grouped by STAU1-low versus STAU1-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STAU1→partner) and Y-score (partner→STAU1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	MRPS15P1 →	+0.107	+4.827	<.001	.002	3	2
READ	MIR3619 →	+1.479	+4.361	<.001	.006	3	2
READ	MIR1273H →	+0.318	+4.653	<.001	.007	3	2
READ	MIR6744 →	+1.267	+4.925	<.001	.004	3	2
READ	MIR7156 →	+0.677	+4.421	<.001	.009	3	2
UCEC	RN7SL248P →	+0.059	+3.059	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,091 associations by consensus.

MRPS15P1 by STAU1 expression — READ

Explore this box plot interactively →