STATH

Across TCGA patient cohorts, STATH protein abundance is significantly associated with the RNA expression of many other genes, with 4,341 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible STATH-associated genes across cancer lineages are KLC3, IRF6, and DNAH7. Each is linked with STATH in more than 1 cancer types. Because this analysis shows association rather than direction, both STATH-to-partner and partner-to-STATH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STATH versus KLC3 in HNSC, with a Pearson correlation of -0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STATH→partner) and Y-score (partner→STATH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	KLC3 →	-0.749	-1.183	.007	<.001	3	1
HNSC	IRF6 →	-0.971	-1.223	.002	.006	3	1
HNSC	DNAH7 →	+0.962	+1.392	.008	.002	3	1
HNSC	TAS2R9 →	+0.633	+1.583	.001	.003	3	1
HNSC	METTL25 →	+0.644	+1.290	<.001	.004	3	1
HNSC	MTRES1 →	+0.581	+1.753	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,341 associations by consensus.

STATH vs KLC3 — HNSC

Explore this scatter interactively →