STATH

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, STATH mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible STATH-associated genes across cancer lineages are CD8+ T-cells. Each is linked with STATH in more than 1 cancer types. Because this analysis shows association rather than direction, both STATH-to-partner and partner-to-STATH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ T-cells grouped by STATH-low versus STATH-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STATH→partner) and Y-score (partner→STATH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUSCCD8+ T-cells →+0.087+4.565<.001.01631
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

CD8+ T-cells by STATH expression — LUSC

Box plot of CD8+ T-cells in STATH-low vs STATH-high samples in LUSC.

Explore this box plot interactively →

Exploration