STAT5B

Across TCGA patient cohorts, STAT5B RNA expression is significantly associated with the protein abundance of many other proteins, with 13,125 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible STAT5B-associated proteins across cancer lineages are CAVIN3, EIF4G1, and KANK2. Each is linked with STAT5B in more than 5 cancer types. Because this analysis shows association rather than direction, both STAT5B-to-partner and partner-to-STAT5B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STAT5B versus CAVIN3 in OV, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (STAT5B→partner) and Y-score (partner→STAT5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CAVIN3 →	+0.779	+0.757	<.001	<.001	3	6
LUAD	EIF4G1 →	-0.243	-0.389	<.001	<.001	3	6
COAD	KANK2 →	+0.527	+0.390	<.001	.001	3	6
OV	LMNB2 →	+0.454	+0.794	<.001	<.001	3	6
OV	SORBS3 →	+0.578	+0.801	<.001	<.001	3	6
CCRCC	YARS1 →	-0.231	-0.187	<.001	.005	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,125 associations by consensus.

STAT5B vs CAVIN3 — OV

Explore this scatter interactively →