STAT5B

Across TCGA patient cohorts, STAT5B protein abundance is significantly associated with the RNA expression of many other genes, with 12,144 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible STAT5B-associated genes across cancer lineages are CXCL12, ASPA, and PTGIS. Each is linked with STAT5B in more than 5 cancer types. Because this analysis shows association rather than direction, both STAT5B-to-partner and partner-to-STAT5B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STAT5B versus CXCL12 in OV, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STAT5B→partner) and Y-score (partner→STAT5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CXCL12 →	+1.535	+0.325	.002	.005	3	6
CCRCC	ASPA →	+0.946	+0.150	.001	<.001	3	6
UCEC	PTGIS →	+1.536	+0.334	<.001	<.001	3	6
HNSC	F13A1 →	+1.493	+0.224	<.001	<.001	3	6
CCRCC	AOX1 →	+1.970	+0.190	<.001	<.001	3	6
UCEC	ABCA8 →	+1.275	+0.341	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,144 associations by consensus.

STAT5B vs CXCL12 — OV

Explore this scatter interactively →