STARD8

Across TCGA patient cohorts, STARD8 protein abundance is significantly associated with the RNA expression of many other genes, with 2,348 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible STARD8-associated genes across cancer lineages are NMNAT3, IFITM2, and THOC3. Each is linked with STARD8 in more than 1 cancer types. Because this analysis shows association rather than direction, both STARD8-to-partner and partner-to-STARD8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STARD8 versus NMNAT3 in CCRCC, with a Pearson correlation of -0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STARD8→partner) and Y-score (partner→STARD8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	NMNAT3 →	-0.802	-0.672	.002	.004	3	2
LSCC	IFITM2 →	+0.837	+0.499	<.001	.009	3	2
LSCC	THOC3 →	-0.871	-0.576	.004	.001	3	2
LSCC	CYTH4 →	+0.763	+0.617	.001	.003	3	1
LSCC	EIF3L →	-0.507	-0.477	.008	.005	3	1
LSCC	PDGFB →	+0.821	+0.500	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,348 associations by consensus.

STARD8 vs NMNAT3 — CCRCC

Explore this scatter interactively →