STARD8

Across TCGA cell cohorts, STARD8 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,906 significant associations in total. BONE shows the largest number of these associations.

The most reproducible STARD8-associated GO terms across cancer lineages are Regulation of cell-substrate junction organization, PML body organization, and Calcium-independent cell-cell adhesion. Each is linked with STARD8 in more than 11 cancer types. Because this analysis shows association rather than direction, both STARD8-to-partner and partner-to-STARD8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cell-substrate junction organization grouped by STARD8-low versus STARD8-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STARD8→partner) and Y-score (partner→STARD8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of cell-substrate junction organization →	+0.160	+1.057	<.001	<.001	3	12
LUNG_NSCLC_LUSC	PML body organization →	+0.244	+1.694	<.001	.004	3	11
LUNG_SCLC	Calcium-independent cell-cell adhesion →	-0.520	-0.772	.003	<.001	3	10
LUNG_NSCLC_LUSC	Endodermal cell fate specification →	-1.800	-1.922	.002	<.001	3	10
LUNG_SCLC	Serotonin secretion →	-1.517	-0.813	<.001	<.001	3	10
LUNG_SCLC	Serotonin production involved in inflammatory response →	-1.517	-0.813	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,906 associations by consensus.

Regulation of cell-substrate junction organization by STARD8 expression — BONE

Explore this box plot interactively →