STARD6

Across TCGA patient cohorts, STARD6 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STARD6-associated genes across cancer lineages are Adipocytes, Th2 cells, and Class-switched memory B-cells. Each is linked with STARD6 in more than 1 cancer types. Because this analysis shows association rather than direction, both STARD6-to-partner and partner-to-STARD6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Adipocytes grouped by STARD6-low versus STARD6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STARD6→partner) and Y-score (partner→STARD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Adipocytes →	+0.023	+2.507	.019	.022	3	2
UCEC	Th2 cells →	+0.242	+3.169	.014	.020	3	1
UCEC	Class-switched memory B-cells →	-0.064	-3.169	.042	.020	1	2
UCEC	Epithelial cells →	-0.105	-3.169	.007	.020	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Adipocytes by STARD6 expression — UCEC

Explore this box plot interactively →