STARD5

Across TCGA patient cohorts, STARD5 mutation is significantly associated with the RNA expression of many other genes, with 59 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STARD5-associated genes across cancer lineages are RN7SKP290, RNA5SP239, and RN7SL584P. Each is linked with STARD5 in more than 1 cancer types. Because this analysis shows association rather than direction, both STARD5-to-partner and partner-to-STARD5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP290 grouped by STARD5-low versus STARD5-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STARD5→partner) and Y-score (partner→STARD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RN7SKP290 →	+0.173	+7.640	<.001	.009	3	1
COAD	RNA5SP239 →	+0.623	+7.741	<.001	.009	3	1
COAD	RN7SL584P →	+1.423	+7.741	<.001	.009	3	1
COAD	RN7SKP260 →	+0.239	+7.741	<.001	.009	3	1
COAD	ZNF519P3 →	+0.039	+7.741	<.001	.009	3	1
COAD	RN7SL722P →	+0.134	+7.741	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 59 associations by consensus.

RN7SKP290 by STARD5 expression — BLCA

Explore this box plot interactively →