STARD3NL

Across TCGA patient cohorts, STARD3NL mutation is significantly associated with the RNA expression of many other genes, with 416 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STARD3NL-associated genes across cancer lineages are DUX4L19, CCL27, and RNA5SP410. Each is linked with STARD3NL in more than 1 cancer types. Because this analysis shows association rather than direction, both STARD3NL-to-partner and partner-to-STARD3NL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DUX4L19 grouped by STARD3NL-low versus STARD3NL-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STARD3NL→partner) and Y-score (partner→STARD3NL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	DUX4L19 →	+0.039	+7.741	<.001	.009	3	2
UCEC	CCL27 →	+0.037	+4.148	<.001	.006	3	2
UCEC	RNA5SP410 →	+0.896	+3.274	<.001	<.001	3	2
UCEC	MRM1 →	+0.645	+3.480	.001	.002	3	1
BLCA	SLC20A1P3 →	+0.049	+7.640	<.001	.009	3	1
BLCA	RNU6-1040P →	+0.343	+7.640	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 416 associations by consensus.

DUX4L19 by STARD3NL expression — COAD

Explore this box plot interactively →