STARD3NL

Across TCGA cell cohorts, STARD3NL mutation is significantly associated with the mutation status of many other genes, with 99 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible STARD3NL-associated genes across cancer lineages are HAO1, F9, and ZP2. Each is linked with STARD3NL in more than 1 cancer types. Because this analysis shows association rather than direction, both STARD3NL-to-partner and partner-to-STARD3NL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HAO1 grouped by STARD3NL-low versus STARD3NL-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STARD3NL→partner) and Y-score (partner→STARD3NL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	HAO1 →	+3.087	+4.392	.005	.005	1	1
LARGE_INTESTINE	F9 →	+5.087	+4.523	.006	.006	1	1
LARGE_INTESTINE	ZP2 →	+3.350	+4.584	.003	.003	1	1
LARGE_INTESTINE	RASL12 →	+5.087	+4.523	.006	.006	1	1
LARGE_INTESTINE	HAMP →	+5.087	+4.523	.006	.006	1	1
LARGE_INTESTINE	CAV2 →	+5.087	+4.523	.006	.006	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 99 associations by consensus.

HAO1 by STARD3NL expression — LARGE_INTESTINE

Explore this box plot interactively →