STARD13

Across TCGA patient cohorts, STARD13 mutation is significantly associated with the RNA expression of many other genes, with 5,150 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STARD13-associated genes across cancer lineages are CMC2, PDZD2, and THRB. Each is linked with STARD13 in more than 3 cancer types. Because this analysis shows association rather than direction, both STARD13-to-partner and partner-to-STARD13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CMC2 grouped by STARD13-low versus STARD13-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STARD13→partner) and Y-score (partner→STARD13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CMC2 →	+0.414	+2.000	<.001	<.001	3	4
UCEC	PDZD2 →	-0.421	-1.350	<.001	<.001	3	4
UCEC	THRB →	-0.554	-1.528	<.001	<.001	3	4
UCEC	TYMSOS →	+0.651	+1.724	<.001	<.001	3	4
UCEC	DEPDC1 →	+0.388	+1.807	.008	.003	3	4
SKCM	CHRNA5 →	+0.421	+3.112	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,150 associations by consensus.

CMC2 by STARD13 expression — UCEC

Explore this box plot interactively →