STAM

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, STAM RNA expression is significantly associated with the protein abundance of many other proteins, with 8,424 significant associations in total. GBM shows the largest number of these associations.

The most reproducible STAM-associated proteins across cancer lineages are CUL2, LARP4B, and UPF2. Each is linked with STAM in more than 5 cancer types. Because this analysis shows association rather than direction, both STAM-to-partner and partner-to-STAM results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STAM versus CUL2 in GBM, with a Pearson correlation of 0.69.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (STAM→partner) and Y-score (partner→STAM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMCUL2 →+0.332+0.518<.001<.00136
GBMLARP4B →+0.304+0.585<.001<.00135
PDACUPF2 →+0.208+0.318<.001<.00135
BRCAKIF5B →+0.198+0.424<.001<.00135
UCECARHGAP21 →+0.316+0.434<.001<.00135
GBMSTAM_S156 →+0.551+0.435<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 8,424 associations by consensus.

STAM vs CUL2 — GBM

Per-sample scatter of STAM vs CUL2 in GBM (Pearson r = 0.69).

Explore this scatter interactively →

Exploration