STAM-AS1

Across TCGA pan-cancer cohorts, STAM-AS1 RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated STAM-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher STAM-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated STAM-AS1 expression acts as an unfavorable survival marker, although some lineages such as THYM and PAAD show a favorable association.

KIRC, THYM, and PAAD are the cancer types where STAM-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.516	0.716	<.001	133	view →
THYM	DFS	Tertile	All	0.902	0.605	.001	41	view →
PAAD	OS	Quartile	All	0.663	0.332	<.001	41	view →
UVM	DFS	Quartile	III,IV	0.184	0.922	<.001	40	view →
MESO	DFS	Median	III,IV	0.203	0.632	.001	36	view →
LIHC	OS	Quartile	All	0.674	0.831	.003	29	view →
READ	OS	Median	III,IV	0.659	0.282	.002	24	view →
SKCM	OS	Quartile	III,IV	0.810	0.574	.007	23	view →
ACC	OS	Median	All	0.692	0.893	.009	22	view →
SARC	DFS	Median	All	0.548	0.706	.005	15	view →
COAD	OS	Median	All	0.487	0.664	.007	14	view →
CESC	DFS	Median	IV	0.307	0.661	.017	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

STAM-AS1–KIRC (OS)

Open the KIRC breakdown →