STAG3L2

Across TCGA patient cohorts, STAG3L2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,199 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible STAG3L2-associated proteins across cancer lineages are GTF2I, MEPCE, and MDH2. Each is linked with STAG3L2 in more than 6 cancer types. Because this analysis shows association rather than direction, both STAG3L2-to-partner and partner-to-STAG3L2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STAG3L2 versus GTF2I in HNSC, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (STAG3L2→partner) and Y-score (partner→STAG3L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	GTF2I →	+0.484	+0.655	<.001	<.001	3	7
GBM	MEPCE →	+0.311	+0.421	<.001	<.001	3	6
PDAC	MDH2 →	+0.320	+0.385	.002	<.001	3	5
LSCC	ZC3HC1 →	+0.207	+0.458	<.001	<.001	3	5
LSCC	ZNF462_S2172 →	+0.661	+0.493	<.001	<.001	3	5
GBM	BUB3 →	+0.276	+0.375	.003	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,199 associations by consensus.

STAG3L2 vs GTF2I — HNSC

Explore this scatter interactively →