STAC2

Across TCGA patient cohorts, STAC2 mutation is significantly associated with the RNA expression of many other genes, with 1,383 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STAC2-associated genes across cancer lineages are RN7SL248P, RNU1-18P, and H3P3. Each is linked with STAC2 in more than 2 cancer types. Because this analysis shows association rather than direction, both STAC2-to-partner and partner-to-STAC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by STAC2-low versus STAC2-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STAC2→partner) and Y-score (partner→STAC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RN7SL248P →	+0.068	+5.263	<.001	.001	3	3
BRCA	RNU1-18P →	+0.515	+5.926	.007	.002	3	2
COAD	H3P3 →	+0.354	+3.730	.008	.004	3	2
CESC	RPS12P10 →	+0.082	+4.124	<.001	.001	3	2
SKCM	FCF1P3 →	+0.116	+3.300	<.001	.004	3	2
BRCA	MIR4778 →	+0.259	+7.471	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,383 associations by consensus.

RN7SL248P by STAC2 expression — CESC

Explore this box plot interactively →