STAB2

Across TCGA cell cohorts, STAB2 mutation is significantly associated with the RNA expression of many other genes, with 687 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible STAB2-associated genes across cancer lineages are TUFM, MARCHF11, and PRR20B. Each is linked with STAB2 in more than 2 cancer types. Because this analysis shows association rather than direction, both STAB2-to-partner and partner-to-STAB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TUFM grouped by STAB2-low versus STAB2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STAB2→partner) and Y-score (partner→STAB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TUFM →	+0.293	+3.321	.003	.002	3	3
SOFT_TISSUE	MARCHF11 →	+0.186	+3.736	.003	.008	3	2
SOFT_TISSUE	PRR20B →	+0.026	+4.392	<.001	.004	3	2
SOFT_TISSUE	PRR20A →	+0.026	+4.392	<.001	.004	3	2
SOFT_TISSUE	PRR20D →	+0.026	+4.392	<.001	.004	3	2
SOFT_TISSUE	PRR20E →	+0.026	+4.392	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 687 associations by consensus.

TUFM by STAB2 expression — LARGE_INTESTINE

Explore this box plot interactively →