ST8SIA5

Across TCGA patient cohorts, ST8SIA5 protein abundance is significantly associated with the RNA expression of many other genes, with 5,725 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ST8SIA5-associated genes across cancer lineages are TOP3B, CRYBB3, and CYP2D6. Each is linked with ST8SIA5 in more than 1 cancer types. Because this analysis shows association rather than direction, both ST8SIA5-to-partner and partner-to-ST8SIA5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ST8SIA5 versus TOP3B in GBM, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST8SIA5→partner) and Y-score (partner→ST8SIA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TOP3B →	-0.303	-0.782	<.001	<.001	3	1
GBM	CRYBB3 →	-0.700	-0.863	<.001	.001	3	1
GBM	CYP2D6 →	-0.466	-0.639	.005	.005	3	1
GBM	SGSM3 →	-0.298	-0.740	.005	.003	3	1
GBM	CST9L →	-0.074	-0.942	.002	.001	3	1
GBM	RBFA →	-0.375	-0.755	.003	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,725 associations by consensus.

ST8SIA5 vs TOP3B — GBM

Explore this scatter interactively →