ST6GALNAC5

Across TCGA patient cohorts, ST6GALNAC5 mutation is significantly associated with the RNA expression of many other genes, with 3,183 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ST6GALNAC5-associated genes across cancer lineages are TEX30, KTI12, and GTF2B. Each is linked with ST6GALNAC5 in more than 2 cancer types. Because this analysis shows association rather than direction, both ST6GALNAC5-to-partner and partner-to-ST6GALNAC5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TEX30 grouped by ST6GALNAC5-low versus ST6GALNAC5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST6GALNAC5→partner) and Y-score (partner→ST6GALNAC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TEX30 →	+0.634	+3.595	<.001	.001	3	3
UCEC	KTI12 →	+0.344	+3.807	.003	<.001	3	3
UCEC	GTF2B →	+0.346	+3.353	.009	.005	3	3
SKCM	ZFPL1 →	+0.371	+3.669	.002	.001	3	3
SKCM	GNG5 →	+0.357	+2.176	.002	.002	3	3
UCEC	PGAP2 →	+0.380	+2.332	.003	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,183 associations by consensus.

TEX30 by ST6GALNAC5 expression — UCEC

Explore this box plot interactively →