ST6GALNAC5

Across TCGA cell cohorts, ST6GALNAC5 mutation is significantly associated with the RNA expression of many other genes, with 28 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ST6GALNAC5-associated genes across cancer lineages are OR4F5, PRSS58, and NANOG. Each is linked with ST6GALNAC5 in more than 1 cancer types. Because this analysis shows association rather than direction, both ST6GALNAC5-to-partner and partner-to-ST6GALNAC5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4F5 grouped by ST6GALNAC5-low versus ST6GALNAC5-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST6GALNAC5→partner) and Y-score (partner→ST6GALNAC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR4F5 →	+0.019	+4.887	<.001	.009	3	2
PANCREAS	PRSS58 →	+0.092	+5.000	<.001	.006	3	1
LARGE_INTESTINE	NANOG →	+0.042	+3.482	.009	.008	3	1
LARGE_INTESTINE	MAGEB4 →	+0.014	+4.000	<.001	<.001	3	1
LARGE_INTESTINE	PPDPFL →	+0.039	+3.217	<.001	.006	3	1
LARGE_INTESTINE	HSFY2 →	+0.011	+3.562	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

OR4F5 by ST6GALNAC5 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →