ST6GALNAC4P1

Across TCGA pan-cancer cohorts, ST6GALNAC4P1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated ST6GALNAC4P1 data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher ST6GALNAC4P1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ST6GALNAC4P1 expression acts as an unfavorable survival marker, although some lineages such as BLCA and HNSC show a favorable association.

COAD, KIRC, and BLCA are the cancer types where ST6GALNAC4P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	0.604	0.781	<.001	107	view →
KIRC	DFS	Quartile	All	0.522	0.748	<.001	57	view →
BLCA	OS	Quartile	All	0.794	0.621	<.001	55	view →
READ	DFS	Median	All	0.399	0.695	<.001	48	view →
HNSC	DFS	Tertile	IV	0.756	0.568	.001	48	view →
ACC	DFS	Median	II,III,IV	0.364	0.694	<.001	39	view →
MESO	OS	Quartile	All	0.278	0.488	.013	24	view →
PRAD	DFS	Tertile	All	0.700	0.932	<.001	14	view →
ESCA	OS	Tertile	IV	0.219	0.856	.024	12	view →
SKCM	OS	Tertile	All	0.398	0.253	.006	10	view →
STAD	DFS	Quartile	II,III,IV	0.432	0.585	.021	8	view →
PAAD	DFS	Median	II,III,IV	0.555	0.368	.016	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

ST6GALNAC4P1–COAD (DFS)

Open the COAD breakdown →