ST6GALNAC4P1

Across TCGA pan-cancer cohorts, ST6GALNAC4P1 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of ST6GALNAC4P1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where ST6GALNAC4P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ST6GALNAC4P1 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

KIRC, LIHC, and BLCA are the cancer types where ST6GALNAC4P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ST6GALNAC4P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	II,III,IV	+0.495	<.001	11	view →
LIHC	All	III,IV	+0.430	<.001	9	view →
BLCA	Female	All	+0.527	.002	8	view →
HNSC	All	All	+0.179	.006	8	view →
COAD	All	All	+0.497	<.001	7	view →
KICH	Female	All	−0.530	<.001	6	view →
THCA	Female	All	+0.426	<.001	6	view →
CHOL	All	All	+1.114	<.001	3	view →
READ	All	All	+0.492	.006	2	view →
STAD	All	II,III,IV	+0.401	.028	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

ST6GALNAC4P1–KIRC

Open the KIRC breakdown →