ST6GALNAC4

Across TCGA patient cohorts, ST6GALNAC4 protein abundance is significantly associated with the RNA expression of many other genes, with 1,005 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ST6GALNAC4-associated genes across cancer lineages are PTGDS, RSPO4, and PXMP4. Each is linked with ST6GALNAC4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ST6GALNAC4-to-partner and partner-to-ST6GALNAC4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ST6GALNAC4 versus PTGDS in LSCC, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST6GALNAC4→partner) and Y-score (partner→ST6GALNAC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PTGDS →	+0.962	+0.671	.004	<.001	3	2
LUAD	RSPO4 →	+0.489	+0.593	<.001	.001	3	1
LUAD	PXMP4 →	+0.853	+0.713	.004	.006	3	1
LUAD	ASPA →	+0.901	+1.047	<.001	.001	3	1
LUAD	RAB5B →	+0.424	+0.622	<.001	<.001	3	1
LUAD	NEDD9 →	+0.713	+0.547	.007	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,005 associations by consensus.

ST6GALNAC4 vs PTGDS — LSCC

Explore this scatter interactively →