ST6GALNAC4

Across TCGA cell cohorts, ST6GALNAC4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,099 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ST6GALNAC4-associated GO terms across cancer lineages are Pigment metabolic process involved in pigmentation, Ganglioside metabolic process, and Metanephric proximal tubule development. Each is linked with ST6GALNAC4 in more than 11 cancer types. Because this analysis shows association rather than direction, both ST6GALNAC4-to-partner and partner-to-ST6GALNAC4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pigment metabolic process involved in pigmentation grouped by ST6GALNAC4-low versus ST6GALNAC4-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ST6GALNAC4→partner) and Y-score (partner→ST6GALNAC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Pigment metabolic process involved in pigmentation →	+0.301	+1.412	<.001	<.001	3	12
BONE	Ganglioside metabolic process →	+0.147	+1.342	<.001	<.001	3	11
URINARY_TRACT	Metanephric proximal tubule development →	+0.237	+1.364	<.001	<.001	2	11
LUNG_NSCLC_LUAD	Ganglioside biosynthetic process →	+0.120	+1.259	<.001	<.001	2	10
BONE	Calcium-independent cell-matrix adhesion →	+0.223	+1.017	<.001	<.001	3	9
SOFT_TISSUE	Carnitine metabolic process, CoA-linked →	+0.215	+1.181	<.001	<.001	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,099 associations by consensus.

Pigment metabolic process involved in pigmentation by ST6GALNAC4 expression — LUNG_SCLC

Explore this box plot interactively →