ST6GALNAC4

Across TCGA cell cohorts, ST6GALNAC4 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ST6GALNAC4-associated genes across cancer lineages are OR1L3, OR14A2, and ZNF831. Each is linked with ST6GALNAC4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ST6GALNAC4-to-partner and partner-to-ST6GALNAC4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1L3 grouped by ST6GALNAC4-low versus ST6GALNAC4-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST6GALNAC4→partner) and Y-score (partner→ST6GALNAC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	OR1L3 →	+0.022	+5.169	<.001	.005	3	1
BREAST	OR14A2 →	+0.035	+5.169	<.001	.005	3	1
LARGE_INTESTINE	ZNF831 →	+0.018	+4.273	<.001	.006	3	1
SKIN	ONECUT3 →	+0.017	+5.029	<.001	.006	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

OR1L3 by ST6GALNAC4 expression — BREAST

Explore this box plot interactively →