ST6GALNAC2

Across TCGA cell cohorts, ST6GALNAC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,840 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ST6GALNAC2-associated GO terms across cancer lineages are Transcription elongation by RNA polymerase I, T cell mediated immunity, and Regulation of mucus secretion. Each is linked with ST6GALNAC2 in more than 9 cancer types. Because this analysis shows association rather than direction, both ST6GALNAC2-to-partner and partner-to-ST6GALNAC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription elongation by RNA polymerase I grouped by ST6GALNAC2-low versus ST6GALNAC2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ST6GALNAC2→partner) and Y-score (partner→ST6GALNAC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Transcription elongation by RNA polymerase I →	-0.104	-3.142	<.001	<.001	3	10
LUNG_NSCLC_LUAD	T cell mediated immunity →	+0.151	+1.452	.001	<.001	3	10
URINARY_TRACT	Regulation of mucus secretion →	+1.113	+2.156	<.001	<.001	3	10
BONE	Negative regulation of NK T cell activation →	+0.830	+0.591	.001	.002	3	9
BREAST	Nucleolar large rRNA transcription by RNA polymerase I →	-0.081	-2.015	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	XMP metabolic process →	-0.137	-1.700	.004	.005	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,840 associations by consensus.

Transcription elongation by RNA polymerase I by ST6GALNAC2 expression — BREAST

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