ST6GALNAC1

Across TCGA patient cohorts, ST6GALNAC1 mutation is significantly associated with the RNA expression of many other genes, with 1,349 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ST6GALNAC1-associated genes across cancer lineages are UBE2Q2P9, MIR7702, and RPL21P31. Each is linked with ST6GALNAC1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ST6GALNAC1-to-partner and partner-to-ST6GALNAC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UBE2Q2P9 grouped by ST6GALNAC1-low versus ST6GALNAC1-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST6GALNAC1→partner) and Y-score (partner→ST6GALNAC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	UBE2Q2P9 →	+0.362	+5.039	<.001	.008	3	3
UCEC	MIR7702 →	+0.214	+4.153	<.001	.005	3	3
SKCM	RPL21P31 →	+0.079	+2.355	<.001	.005	3	3
CESC	RNA5SP198 →	+0.305	+5.144	<.001	.003	3	3
SKCM	RN7SL134P →	+0.078	+2.855	<.001	.001	3	3
READ	RNU6-212P →	+0.839	+5.219	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,349 associations by consensus.

UBE2Q2P9 by ST6GALNAC1 expression — READ

Explore this box plot interactively →