ST6GALNAC1

Across TCGA cell cohorts, ST6GALNAC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,471 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ST6GALNAC1-associated GO terms across cancer lineages are Negative regulation of T cell mediated cytotoxicity, Positive regulation of endoplasmic reticulum unfolded protein response, and Sensory perception of salty taste. Each is linked with ST6GALNAC1 in more than 9 cancer types. Because this analysis shows association rather than direction, both ST6GALNAC1-to-partner and partner-to-ST6GALNAC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of T cell mediated cytotoxicity grouped by ST6GALNAC1-low versus ST6GALNAC1-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ST6GALNAC1→partner) and Y-score (partner→ST6GALNAC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Negative regulation of T cell mediated cytotoxicity →	+1.609	+0.977	<.001	.001	3	10
UPPER_AERODIGESTIVE_TRACT	Positive regulation of endoplasmic reticulum unfolded protein response →	+0.128	+2.025	<.001	<.001	3	10
OVARY	Sensory perception of salty taste →	+1.316	+2.259	<.001	<.001	3	10
STOMACH	Regulation of action potential →	+0.149	+3.371	<.001	<.001	3	9
STOMACH	Hexose phosphate transport →	+0.221	+3.448	<.001	<.001	3	9
STOMACH	Glucose-6-phosphate transport →	+0.221	+3.448	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,471 associations by consensus.

Negative regulation of T cell mediated cytotoxicity by ST6GALNAC1 expression — SKIN

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