ST6GALNAC1

Across TCGA cell cohorts, ST6GALNAC1 mutation is significantly associated with the RNA expression of many other genes, with 113 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ST6GALNAC1-associated genes across cancer lineages are SLC22A8, OR10A2, and OR11H6. Each is linked with ST6GALNAC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ST6GALNAC1-to-partner and partner-to-ST6GALNAC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC22A8 grouped by ST6GALNAC1-low versus ST6GALNAC1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST6GALNAC1→partner) and Y-score (partner→ST6GALNAC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SLC22A8 →	+0.016	+4.507	.005	.001	3	1
BLOOD_Leukemia	OR10A2 →	+0.046	+3.807	.008	.008	3	1
BLOOD_Leukemia	OR11H6 →	+0.028	+3.705	<.001	.007	3	1
LARGE_INTESTINE	MTMR3 →	+0.749	+3.064	.002	.009	3	1
LARGE_INTESTINE	SAMM50 →	+0.660	+3.064	<.001	.009	3	1
LARGE_INTESTINE	SLC35F2 →	+0.849	+3.247	.002	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 113 associations by consensus.

SLC22A8 by ST6GALNAC1 expression — BLOOD_Leukemia

Explore this box plot interactively →