ST3GAL6

Across TCGA patient cohorts, ST3GAL6 protein abundance is significantly associated with the RNA expression of many other genes, with 2,066 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible ST3GAL6-associated genes across cancer lineages are C5orf46, TRIM69, and RN7SL19P. Each is linked with ST3GAL6 in more than 1 cancer types. Because this analysis shows association rather than direction, both ST3GAL6-to-partner and partner-to-ST3GAL6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ST3GAL6 versus C5orf46 in LSCC, with a Pearson correlation of 0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST3GAL6→partner) and Y-score (partner→ST3GAL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	C5orf46 →	+1.022	+0.941	.001	<.001	3	2
UCEC	TRIM69 →	-0.821	-0.955	.006	<.001	3	2
LUAD	RN7SL19P →	-0.806	-0.511	.003	.006	3	2
PDAC	CTNNA1P1 →	-0.386	-1.100	<.001	.003	3	2
UCEC	STARD3 →	-0.682	-0.568	.009	.002	3	2
GBM	TOM1L1 →	-0.786	-0.465	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,066 associations by consensus.

ST3GAL6 vs C5orf46 — LSCC

Explore this scatter interactively →