ST3GAL6

Across TCGA cell cohorts, ST3GAL6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,959 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ST3GAL6-associated GO terms across cancer lineages are Substrate adhesion-dependent cell spreading, Detection of external stimulus, and Type 2 mitophagy. Each is linked with ST3GAL6 in more than 9 cancer types. Because this analysis shows association rather than direction, both ST3GAL6-to-partner and partner-to-ST3GAL6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Substrate adhesion-dependent cell spreading grouped by ST3GAL6-low versus ST3GAL6-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ST3GAL6→partner) and Y-score (partner→ST3GAL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Substrate adhesion-dependent cell spreading →	+0.143	+1.072	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Detection of external stimulus →	-0.105	-1.135	<.001	<.001	3	8
BREAST	Type 2 mitophagy →	+0.176	+1.191	.002	.001	3	8
STOMACH	Positive regulation of autophagosome assembly →	+0.091	+1.405	.002	.005	3	8
LUNG_NSCLC_LUSC	Regulation of protein localization to mitochondrion →	+0.146	+1.381	.002	.001	3	8
URINARY_TRACT	Protoporphyrinogen IX biosynthetic process →	+0.122	+1.340	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,959 associations by consensus.

Substrate adhesion-dependent cell spreading by ST3GAL6 expression — SOFT_TISSUE

Explore this box plot interactively →