ST3GAL6

Across TCGA cell cohorts, ST3GAL6 mutation is significantly associated with the RNA expression of many other genes, with 168 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ST3GAL6-associated genes across cancer lineages are C1orf94, CA2, and MTMR9. Each is linked with ST3GAL6 in more than 1 cancer types. Because this analysis shows association rather than direction, both ST3GAL6-to-partner and partner-to-ST3GAL6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C1orf94 grouped by ST3GAL6-low versus ST3GAL6-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST3GAL6→partner) and Y-score (partner→ST3GAL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	C1orf94 →	+0.450	+4.199	<.001	.007	3	1
LARGE_INTESTINE	CA2 →	+2.002	+3.212	<.001	.006	3	1
LARGE_INTESTINE	MTMR9 →	+0.583	+3.212	.001	.006	3	1
LARGE_INTESTINE	FUBP3 →	+0.440	+3.299	.007	.004	3	1
LARGE_INTESTINE	GTF2H3 →	+0.735	+3.299	.002	.004	3	1
LARGE_INTESTINE	C6orf118 →	+0.087	+2.378	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 168 associations by consensus.

C1orf94 by ST3GAL6 expression — BREAST

Explore this box plot interactively →