ST3GAL6-AS1

Across TCGA pan-cancer cohorts, ST3GAL6-AS1 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated ST3GAL6-AS1 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher ST3GAL6-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ST3GAL6-AS1 expression acts as an unfavorable survival marker, although some lineages such as UVM and LUAD show a favorable association.

BLCA, UVM, and STAD are the cancer types where ST3GAL6-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Median	All	0.337	0.530	<.001	117	view →
UVM	DFS	Quartile	All	0.808	0.390	<.001	55	view →
STAD	OS	Median	All	0.382	0.659	<.001	53	view →
LUAD	DFS	Quartile	III,IV	0.674	0.254	.007	27	view →
LAML	DFS	Tertile	All	0.693	0.460	.005	26	view →
LUSC	OS	Quartile	III,IV	0.217	0.601	.002	24	view →
KIRP	DFS	Tertile	III,IV	0.708	0.084	.003	24	view →
MESO	OS	Quartile	All	0.691	0.460	.008	23	view →
GBM	DFS	Quartile	All	0.331	0.170	.001	19	view →
KIRC	DFS	Quartile	All	0.831	0.568	.016	16	view →
PAAD	OS	Median	II,III,IV	0.678	0.442	<.001	14	view →
READ	DFS	Quartile	III,IV	0.202	0.679	.017	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

ST3GAL6-AS1–BLCA (OS)

Open the BLCA breakdown →