ST3GAL6-AS1

Across TCGA pan-cancer cohorts, ST3GAL6-AS1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of ST3GAL6-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where ST3GAL6-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types ST3GAL6-AS1 is over-expressed in tumor, although a few such as KIRC and KIRP show the opposite, repressed pattern.

KIRC, KIRP, and LUAD are the cancer types where ST3GAL6-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ST3GAL6-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	−1.478	<.001	12	view →
KIRP	All	III,IV	−1.450	<.001	11	view →
LUAD	Male	II,III,IV	−0.796	<.001	8	view →
HNSC	Female	III,IV	+0.863	<.001	6	view →
BRCA	All	III,IV	−0.724	<.001	6	view →
COAD	All	All	−0.233	.002	4	view →
THCA	Male	III,IV	−1.005	.008	3	view →
UCEC	All	All	−0.668	.004	2	view →
LUSC	All	III,IV	−0.530	.002	2	view →
PRAD	All	All	−0.258	<.001	2	view →
READ	Female	All	−0.972	.035	1	view →
STAD	All	All	−0.297	.041	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

ST3GAL6-AS1–KIRC

Open the KIRC breakdown →