ST3GAL5

Across TCGA patient cohorts, ST3GAL5 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,851 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ST3GAL5-associated proteins across cancer lineages are ARHGEF6, CLIC2, and TBC1D2B. Each is linked with ST3GAL5 in more than 7 cancer types. Because this analysis shows association rather than direction, both ST3GAL5-to-partner and partner-to-ST3GAL5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ST3GAL5 versus ARHGEF6 in LSCC, with a Pearson correlation of 0.63.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ST3GAL5→partner) and Y-score (partner→ST3GAL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ARHGEF6 →	+0.431	+0.703	<.001	<.001	3	8
LSCC	CLIC2 →	+0.636	+0.713	<.001	<.001	3	8
OV	TBC1D2B →	+0.320	+0.540	.002	.003	2	8
CCRCC	DOCK11 →	+0.498	+0.728	<.001	<.001	3	7
UCEC	ESF1_S153 →	-0.955	-0.854	<.001	<.001	3	7
LSCC	DOCK2 →	+0.513	+0.770	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,851 associations by consensus.

ST3GAL5 vs ARHGEF6 — LSCC

Explore this scatter interactively →