ST3GAL5-AS1

Across TCGA pan-cancer cohorts, ST3GAL5-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated ST3GAL5-AS1 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher ST3GAL5-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated ST3GAL5-AS1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and BLCA show a favorable association.

LUAD, BLCA, and ACC are the cancer types where ST3GAL5-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	All	0.779	0.591	<.001	79	view →
BLCA	DFS	Median	All	0.592	0.430	<.001	77	view →
ACC	DFS	Median	All	0.398	0.756	<.001	57	view →
LUSC	DFS	Median	All	0.331	0.459	.001	54	view →
UCS	DFS	Tertile	All	0.410	0.127	.009	48	view →
PAAD	DFS	Tertile	All	0.433	0.265	.002	44	view →
MESO	OS	Tertile	All	0.504	0.249	.002	41	view →
KIRP	DFS	Tertile	II,III,IV	0.202	0.858	<.001	38	view →
KIRC	DFS	Tertile	II,III,IV	0.424	0.589	.013	25	view →
ESCA	DFS	Tertile	II,III,IV	0.651	0.460	.014	22	view →
KICH	DFS	Median	III,IV	0.439	0.882	.024	15	view →
SARC	DFS	Tertile	All	0.688	0.538	.008	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

ST3GAL5-AS1–LUAD (OS)

Open the LUAD breakdown →