ST3GAL4

Across TCGA cell cohorts, ST3GAL4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,494 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ST3GAL4-associated GO terms across cancer lineages are Positive regulation of leukocyte tethering or rolling, Regulation of leukocyte tethering or rolling, and Sialylation. Each is linked with ST3GAL4 in more than 12 cancer types. Because this analysis shows association rather than direction, both ST3GAL4-to-partner and partner-to-ST3GAL4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of leukocyte tethering or rolling grouped by ST3GAL4-low versus ST3GAL4-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ST3GAL4→partner) and Y-score (partner→ST3GAL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Positive regulation of leukocyte tethering or rolling →	+1.519	+1.857	.002	.001	3	13
OVARY	Regulation of leukocyte tethering or rolling →	+0.928	+1.497	.001	<.001	2	11
LARGE_INTESTINE	Sialylation →	+0.748	+1.899	<.001	<.001	3	9
URINARY_TRACT	Very long-chain fatty acid catabolic process →	+0.112	+1.675	<.001	<.001	3	8
STOMACH	Negative regulation of membrane protein ectodomain proteolysis →	+0.194	+2.296	<.001	.001	3	8
UPPER_AERODIGESTIVE_TRACT	Meiotic chromosome condensation →	+0.130	+0.808	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,494 associations by consensus.

Positive regulation of leukocyte tethering or rolling by ST3GAL4 expression — LIVER

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