ST3GAL4

Across TCGA cell cohorts, ST3GAL4 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ST3GAL4-associated genes across cancer lineages are OR10K2, OR10T2, and KRT85. Each is linked with ST3GAL4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ST3GAL4-to-partner and partner-to-ST3GAL4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10K2 grouped by ST3GAL4-low versus ST3GAL4-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST3GAL4→partner) and Y-score (partner→ST3GAL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	OR10K2 →	+0.047	+4.781	<.001	.003	3	1
BREAST	OR10T2 →	+0.137	+4.781	<.001	.003	3	1
LARGE_INTESTINE	KRT85 →	+0.414	+3.145	<.001	.004	3	1
LARGE_INTESTINE	CFHR2 →	+0.032	+3.700	<.001	.009	3	1
LARGE_INTESTINE	ZSCAN4 →	+0.325	+3.617	.008	.004	1	1
LARGE_INTESTINE	MYT1L →	+0.160	+3.333	.006	.009	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

OR10K2 by ST3GAL4 expression — BREAST

Explore this box plot interactively →