ST3GAL3

Across TCGA patient cohorts, ST3GAL3 protein abundance is significantly associated with the RNA expression of many other genes, with 786 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ST3GAL3-associated genes across cancer lineages are TTLL12, PNPLA3, and SPTLC2. Each is linked with ST3GAL3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ST3GAL3-to-partner and partner-to-ST3GAL3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ST3GAL3 versus TTLL12 in COAD, with a Pearson correlation of -0.83.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST3GAL3→partner) and Y-score (partner→ST3GAL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TTLL12 →	-1.282	-0.436	<.001	.001	3	1
COAD	PNPLA3 →	-2.110	-0.596	<.001	.003	3	1
COAD	SPTLC2 →	-1.139	-0.436	.004	.001	3	1
COAD	ITPK1 →	-0.686	-0.444	.002	.001	3	1
COAD	TELO2 →	-0.978	-0.435	<.001	.001	3	1
COAD	STUB1 →	-0.468	-0.412	.002	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 786 associations by consensus.

ST3GAL3 vs TTLL12 — COAD

Explore this scatter interactively →