ST3GAL3-AS1

Across TCGA pan-cancer cohorts, ST3GAL3-AS1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated ST3GAL3-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher ST3GAL3-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ST3GAL3-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and THCA show a favorable association.

ACC, KIRC, and DLBC are the cancer types where ST3GAL3-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.261	0.638	<.001	79	view →
KIRC	OS	Tertile	All	0.478	0.706	.002	68	view →
DLBC	DFS	Median	IV	0.223	1.000	.001	68	view →
THYM	DFS	Median	II,III,IV	0.702	1.000	.001	42	view →
UCEC	DFS	Quartile	IV	0.867	0.276	.006	28	view →
SKCM	DFS	Tertile	All	0.651	0.844	.007	24	view →
THCA	DFS	Median	All	0.898	0.770	.009	22	view →
READ	DFS	Tertile	IV	0.095	0.697	.014	18	view →
CHOL	DFS	Tertile	II,III,IV	0.796	0.134	.015	14	view →
PAAD	OS	Quartile	All	0.696	0.450	.021	10	view →
LUSC	OS	Tertile	All	0.825	0.720	.004	10	view →
LUAD	DFS	Quartile	III,IV	0.841	0.417	.006	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

ST3GAL3-AS1–ACC (DFS)

Open the ACC breakdown →