ST3GAL1

Across TCGA patient cohorts, ST3GAL1 mutation is significantly associated with the RNA expression of many other genes, with 803 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ST3GAL1-associated genes across cancer lineages are VN1R54P, GMCL1P2, and RNU6-1147P. Each is linked with ST3GAL1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ST3GAL1-to-partner and partner-to-ST3GAL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VN1R54P grouped by ST3GAL1-low versus ST3GAL1-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST3GAL1→partner) and Y-score (partner→ST3GAL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	VN1R54P →	+0.384	+4.377	<.001	.001	3	3
CESC	GMCL1P2 →	+0.298	+4.364	<.001	.006	3	2
COAD	RNU6-1147P →	+0.506	+3.452	<.001	.009	3	2
COAD	RNU6-955P →	+0.679	+3.652	<.001	.003	3	2
READ	RNU7-43P →	+0.447	+5.257	<.001	.002	3	2
CESC	OR5T2 →	+0.044	+6.164	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 803 associations by consensus.

VN1R54P by ST3GAL1 expression — LUAD

Explore this box plot interactively →