ST20

Across TCGA cell cohorts, ST20 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,259 significant associations in total. CNS shows the largest number of these associations.

The most reproducible ST20-associated GO terms across cancer lineages are Response to UV-C, Regulation of proteasomal protein catabolic process, and mRNA catabolic process. Each is linked with ST20 in more than 12 cancer types. Because this analysis shows association rather than direction, both ST20-to-partner and partner-to-ST20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to UV-C grouped by ST20-low versus ST20-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ST20→partner) and Y-score (partner→ST20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Response to UV-C →	+0.113	+1.452	.003	.001	3	13
BLOOD_Lymphoma	Regulation of proteasomal protein catabolic process →	+0.032	+0.640	.008	.002	3	7
OESOPHAGUS	mRNA catabolic process →	+0.083	+1.288	<.001	.007	3	7
LUNG_SCLC	Protein localization to site of double-strand break →	+0.074	+0.541	.001	.002	3	7
OESOPHAGUS	RNA splicing, via transesterification reactions →	+0.098	+1.568	.001	.006	3	6
STOMACH	Mitochondrial electron transport, cytochrome c to oxygen →	+0.097	+0.840	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,259 associations by consensus.

Response to UV-C by ST20 expression — OESOPHAGUS

Explore this box plot interactively →