ST20

Across TCGA cell cohorts, ST20 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible ST20-associated genes across cancer lineages are OR12D3 and DEFA6. Each is linked with ST20 in more than 1 cancer types. Because this analysis shows association rather than direction, both ST20-to-partner and partner-to-ST20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR12D3 grouped by ST20-low versus ST20-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST20→partner) and Y-score (partner→ST20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	OR12D3 →	+0.016	+5.807	<.001	.001	3	1
OVARY	DEFA6 →	+0.111	+5.196	.004	.005	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OR12D3 by ST20 expression — OVARY

Explore this box plot interactively →