ST20-AS1

Across TCGA pan-cancer cohorts, ST20-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated ST20-AS1 data layer.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher ST20-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated ST20-AS1 expression acts as an unfavorable survival marker, although some lineages such as PAAD and KIRP show a favorable association.

PAAD, LGG, and CESC are the cancer types where ST20-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PAAD	OS	Median	All	0.552	0.263	<.001	69	view →
LGG	DFS	Median	All	0.652	0.825	<.001	54	view →
CESC	DFS	Quartile	IV	0.270	0.798	.010	36	view →
BRCA	DFS	Quartile	II,III,IV	0.840	0.932	<.001	33	view →
UVM	DFS	Quartile	III,IV	0.446	1.000	.001	31	view →
BLCA	DFS	Quartile	All	0.496	0.644	.005	29	view →
ACC	DFS	Median	All	0.533	0.780	.003	29	view →
KIRP	OS	Median	All	0.958	0.805	.019	23	view →
LIHC	OS	Median	III,IV	0.771	0.453	.002	20	view →
SKCM	OS	Median	III,IV	0.601	0.774	.009	18	view →
ESCA	OS	Quartile	III,IV	0.704	0.335	.036	14	view →
MESO	DFS	Quartile	II,III,IV	0.319	0.783	.026	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

ST20-AS1–PAAD (OS)

Open the PAAD breakdown →