ST13P4

Across TCGA patient cohorts, ST13P4 mutation is significantly associated with the total protein of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ST13P4-associated genes across cancer lineages are EGFR, Lck, and PCNA. Each is linked with ST13P4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ST13P4-to-partner and partner-to-ST13P4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EGFR grouped by ST13P4-low versus ST13P4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST13P4→partner) and Y-score (partner→ST13P4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR →	-0.202	-3.000	.028	.037	3	1
UCEC	Lck →	+0.314	+3.000	.006	.037	2	1
UCEC	PCNA →	+0.299	+3.000	.016	.037	2	1
UCEC	Shc_pY317 →	-0.194	-3.000	.027	.037	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

EGFR by ST13P4 expression — UCEC

Explore this box plot interactively →